Oleg Mirzov
System architect
Decoration of amyloid fibrils with luminescent conjugated polymers
Author
Summary, in English
In this work we report the coating of a biological template with a polar, but uncharged,luminescent conjugated polymer, soluble in organic solvents but not in water, to produce a nanowire. Amyloid fibrils from bovine insulin were decorated with an alternating polyfluorene derivative. Decorated fibrils were partially aligned on hydrophobic surfaces as separate and
bundled fibrils, by means of molecular combing. The single molecule spectroscopy technique utilizing excitation by rotating linearly polarized light and fluorescence detection through a rotating polarizer showed a high degree of anisotropy of the polymer chains on the individual fibrils. The high degree of polarization indicated highly oriented polymer chains with the preferential orientation of the polymer backbone along the fibrils. The anisotropy ratios are
comparable with those of well-oriented polymer chains in films.
bundled fibrils, by means of molecular combing. The single molecule spectroscopy technique utilizing excitation by rotating linearly polarized light and fluorescence detection through a rotating polarizer showed a high degree of anisotropy of the polymer chains on the individual fibrils. The high degree of polarization indicated highly oriented polymer chains with the preferential orientation of the polymer backbone along the fibrils. The anisotropy ratios are
comparable with those of well-oriented polymer chains in films.
Department/s
- Chemical Physics
Publishing year
2008
Language
English
Pages
126-132
Publication/Series
Journal of Materials Chemistry
Volume
18
Document type
Journal article
Publisher
Royal Society of Chemistry
Topic
- Atom and Molecular Physics and Optics
Status
Published
ISBN/ISSN/Other
- ISSN: 1364-5501