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Oleg Mirzov

System architect

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Decoration of amyloid fibrils with luminescent conjugated polymers

Author

  • Anna Herland
  • Daniel Thomsson
  • Oleg Mirzov
  • Ivan Scheblykin
  • Olle Inganäs

Summary, in English

In this work we report the coating of a biological template with a polar, but uncharged,luminescent conjugated polymer, soluble in organic solvents but not in water, to produce a nanowire. Amyloid fibrils from bovine insulin were decorated with an alternating polyfluorene derivative. Decorated fibrils were partially aligned on hydrophobic surfaces as separate and

bundled fibrils, by means of molecular combing. The single molecule spectroscopy technique utilizing excitation by rotating linearly polarized light and fluorescence detection through a rotating polarizer showed a high degree of anisotropy of the polymer chains on the individual fibrils. The high degree of polarization indicated highly oriented polymer chains with the preferential orientation of the polymer backbone along the fibrils. The anisotropy ratios are

comparable with those of well-oriented polymer chains in films.

Department/s

  • Chemical Physics

Publishing year

2008

Language

English

Pages

126-132

Publication/Series

Journal of Materials Chemistry

Volume

18

Document type

Journal article

Publisher

Royal Society of Chemistry

Topic

  • Atom and Molecular Physics and Optics

Status

Published

ISBN/ISSN/Other

  • ISSN: 1364-5501